Gastrinoma

A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1).

Also Known As:

Ulcerogenic Islet Cell Tumor; Gastrin Producing Tumor; Gastrin-Producing Tumors; Gastrinomas; Tumor, Gastrin-Producing; Tumors, Gastrin-Producing; Gastrin-Producing Tumor; Islet Cell Tumor, Ulcerogenic

Neoplasms: 1361496
- Neoplasms by Site: 4
  - Digestive System Neoplasms: 251
    - Pancreatic Neoplasms: 35273
      - Islet Cell Carcinoma: 161
        Gastrinoma: 882
  - Endocrine Gland Neoplasms: 135
    - Pancreatic Neoplasms: 35273
      - Islet Cell Carcinoma: 161
        Gastrinoma: 882
- Neoplasms by Histologic Type: 2
  - Glandular and Epithelial Neoplasms: 445
    - Carcinoma: 143226
      - Adenocarcinoma: 59622
        Islet Cell Carcinoma: 161
        Gastrinoma: 882
Digestive System Diseases: 1068
- Pancreatic Diseases: 1654
  - Pancreatic Neoplasms: 35273
    - Islet Cell Carcinoma: 161
      - Gastrinoma: 882
- Digestive System Neoplasms: 251
  - Pancreatic Neoplasms: 35273
    - Islet Cell Carcinoma: 161
      - Gastrinoma: 882
Endocrine System Diseases: 996
- Endocrine Gland Neoplasms: 135
  - Pancreatic Neoplasms: 35273
    - Islet Cell Carcinoma: 161
      - Gastrinoma: 882

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